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Current Legislation in the UK

The Veterinary Medicines Directive has stated that any CBD Oil product on sale in the UK specifically for animals must have a Medicines Authorisation Number in order to be legally offered for sale. Presently no CBD Oil products are currently licensed in the UK. However, MsRCVS are allowed under the terms of Cascade (which governs medicines use for animals in the UK) to prescribe and supply CBD Oil for veterinary use where appropriate and where other Licensed options are either not working or are not appropriate.

If you would like a consultation with Roger to discuss your animal's needs on a case by case basis, please contact Roger for an appointment. Roger will have to see your animal and discuss the current situation in person in order to comply with the above requirements.

For those who do not know about CBD and the endocannabinoid system would like to know more there is further information below.

In 1992, when scientists started investigating the beneficial effects of THC and CBD, they discovered a new biochemical communication system in the body — now called the endocannabinoid system. We are still discovering new things about this body system but it’s believed to be one of the most important physiological systems involved in maintaining the health of the body. It plays a role in maintaining homeostasis, ensuring that the body has a stable and well-functioning internal environment.

The system is made up of endocannabinoid receptors that respond to cannabinoid compounds found in the cannabis plant species and a number of other plants. These receptors are found throughout the brain and body. Of the 100+ cannabinoids that have been identified in the cannabis species, CBD and THC have been studied the most extensively for their role in the endocannabinoid system.

Researchers have identified two major types of cannabinoid receptors — CB1 and CB2. Additional receptors for cannabinoids exist but we currently know little about them at present. CB1 receptors are found in the brain and central nervous system, and CB2 receptors are found in our immune cells. In fact, recent discoveries suggest that more than half of all the receptors in the brain are cannabinoid receptors which is why CBD has been found to help with brain conditions such as epilepsy.

We have what’s called “endogenous cannabinoids,” which are neurotransmitters, or chemical messengers, that bind to cannabinoid receptors. But compounds found in cannabis, like THC, also bind to cannabinoid receptors, mimicking the effects of messengers found within the human body. Receptors react to cannabis compounds and produce a specific effect, which can benefit many body parts and bodily processes.

CBD doesn’t act as a messenger for CB1 or CB2 as THC does, but it does modulate several non-cannabinoid receptors, including serotonin and TRPV1, which can influence pain perception. It also may activate receptors associated with cancer, cardiovascular disease and Alzheimer’s disease.

So what happens when the endocannabinoid system becomes underactive or overactive? The body will begin to malfunction and can no longer remain in a homeostatic state. This is being referred to as “clinical endocannabinoid deficiency,” and it may lead to health problems like chronic pain, fatigue, inflammation, arthritis, autoimmune disease and mood disorders.

Just like any other body system, endocannabinoid deficiency can be the result of dietary choices, lifestyle factors and other issues. Using CBD and other compounds found in full spectrum CBD Oil helps rebalance the endocannabinoid system to deliver extremely therapeutic effects.

The biggest concern for people when they first hear about CBD beginners is whether or not it causes psychoactive effects. Many people have heard of the many CBD oil benefits but automatically think of marijuana and don't appreciate that CBD Oil is different and it is possible to obtain the therapeutic benefits without feeling “high” after using it.

To get it straight from the start, there is a family of Cannabis plants of which Marijuana is just one. Hemp is another. There are others. All plants from this family produce and contain a range of chemicals called Cannabinoids of which CBD is one and THC (tretrahydrocannabidiol) is another. THC is found in Marijuana and causes the psychoactive effect of the "high". Hemp produces both but very low amounts of THC. THC and CBD have some cross-over in terms of beneficial effects too, however log term use of THC can cause adverse psychiatric problems which of course we don't want.

There are 2 different ways to separate the CBD from the THC which results in 2 different forms of CBD Oil on the market as result.

  1. The first method is to extract the CBD as an isolate which is CBD in it's purest form.
  2. The second method is to extract the THC, leaving the full spectrum CBD Oil behind.

On the face of it you'd think they both end up with the same CBD Oil but there is a very important difference. In herbalism, although there may appear to be one main active ingredient there are other compounds in the whole plant that often modulate the effect of the identified main ingredient which can improve the bioavailability of the active substance and/or modify it's action to help reduce or prevent adverse effects. This is called the Entourage Effect. When we consider that Hemp contains a wide variety of other compounds it is easy to see that method 2 which results in a full spectrum CBD Oil is the best option. This is what Roger uses because it has a fuller action and better bioavailability. It includes the following

Cannabinoids

Whilst CBD is what people are most focussed on, there are plenty of unheralded cannabinoids that offer relief.

Cannabigerol (CBG)

Also known as the ‘stem cell’ cannabinoid, most CBG is transformed into cannabinoids such as CBD and THC by the plant. As a result, most processed plants have a low level of CBG.

Cannabichromene

(CBC)

It is probably the least studied ‘major’ cannabinoid even though it is rather abundant in certain marijuana strains. As such, there isn’t enough data available to suggest it offers the same remarkable benefits as CBD. However, the research that is available suggests that CBC has antidepressant, pain relieving, and anti-anxiety effects.

Lesser known cannabinoids include:

Cannabicyclol (CBL)
Cannabitriol (CBT)
Cannabicitran (CBT)
Cannabifuran (CBF)

Terpenes

Terpenes are aromatic chemicals that give the cannabis plant its unique scent. Even in tiny amounts, terpenes work extremely well with cannabinoids to heal the body. Here are some well-known terpenes:

Limonene
This stress reliever also helps boost your mood. You can even rely on it to assist with gastric flux issues.

Pinene
It could potentially improve your memory and boost alertness. It is also anti-inflammatory.

Linalool
This has a sedative effect and works to help patients with depression, insomnia, and stress.

Caryophyllene
This terpene is an antioxidant and anti-inflammatory that helps relieve the symptoms of pain. It is also useful against insomnia.

Humulene
This is another pain-relieving terpene which has antibacterial properties and also works as an appetite suppressant.

Vitamins & Minerals

Full spectrum CBD oil contains vitamins A, C, & E along with complex B vitamins such as niacin, riboflavin, and thiamine. An increasing number of people don’t consume beta-carotene, but it is abundant in full spectrum oil. Crucial minerals contained in this oil include zinc, potassium, iron, calcium, and phosphorus.

Essential Fats & Protein

If all of the above wasn’t enough, full spectrum CBD oil contains up to 20 amino acids including the nine essential ones. Essential fatty acids such as Omega 3 and Omega 6, which help promote better heart health, are included in the optimal 3:1 ratio. Hemp oil is even a good source of protein which helps repair and build tissues.

The Entourage Effect

The Entourage Effect is the beneficial effect produced from the synergistic interaction of the cannabinoids, flavonoids, terpenes, and fatty acids naturally found in full spectrum CBD Oil. A synergistic effect is where there are additional benefits from all these compounds working together compared with ingesting one component at a time. The products Roger uses are full spectrum which takes advantage of the entourage effect and has more activity than CBD products based on extracting just the CBD as an isolate.

A plant such as Hemp from the Cannabis genus of plants contains approximately 500 active compounds. This includes about 100 phytocannabinoids (including THC and CBD in varying amounts in each different species). Other significant classes of compounds found in cannabis plants are terpenes, flavonoids, and fatty acids.

Flavonoids are phytonutrients which are responsible for the vivid non-green colours we see in plants. The colour of those shiny red apples and beautiful blueberries is all due to their unique flavonoid profile. Commonly known flavonoids include catechins (found in green tea) and quercetin (found in cannabis, fruits, and vegetables). Flavonoids are known to have antiviral, antioxidant, and anti-inflammatory effects, especially the ones found in Cannabis species.

The Best CBD Oil Products are Full Plant Extracts

Health practitioners who use Cannabis medicines in their practice recognise the increased benefits from using products that embrace the Entourage Effect. Responses are better to full spectrum CBD oil products which contain multiple cannabinoids as opposed to single cannabinoids in isolation. This finding is also applicable to cannabinoids found in nature as opposed to those produced synthetically in a chemistry lab which will typically be isolates.